STAT3 Pre-design Chimera RNAi-RNAi技术-试剂-生物在线
亚诺法生技股份有限公司(Abnova)
STAT3 Pre-design Chimera RNAi

STAT3 Pre-design Chimera RNAi

商家询价

产品名称: STAT3 Pre-design Chimera RNAi

英文名称: STAT3 Pre-design Chimera RNAi

产品编号: H00006774-R02

产品价格: 0

产品产地: 台湾

品牌商标: Abnova

更新时间: null

使用范围: null

亚诺法生技股份有限公司(Abnova)
  • 联系人 :
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  • 邮编 : 11493
  • 所在区域 : 台湾
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  • 邮箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_139276
  • Target Region:
  • Coding sequence
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 6774
  • Gene Name:
  • STAT3
  • Gene Alias:
  • APRF,FLJ20882,HIES,MGC16063
  • Gene Description:
  • signal transducer and activator of transcription 3 (acute-phase response factor)
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • DNA-binding protein APRF,acute-phase response factor,signal transducer and activator of transcription 3

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