FITC标记的9号染色体开放阅读框91抗体
产品名称： FITC标记的9号染色体开放阅读框91抗体
英文名称： Anti-C9ORF91/FITC
产品编号： HZ-15347R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-C9ORF91/FITC Conjugated antibody
FITC标记的9号染色体开放阅读框91抗体
| 英文名称 | Anti-C9ORF91/FITC |
| 中文名称 | FITC标记的9号染色体开放阅读框91抗体 |
| 别 名 | C9orf91; Chromosome 9 open reading frame 91; CI091_HUMAN; RP11-402G3.2; Transmembrane protein C9orf91. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 38kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C9ORF91 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf91 gene product has been provisionally designated C9orf91 pending further characterization. There are three isoforms of C9orf91 that are produced as a result of alternative splicing events. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Database links: UniProtKB/Swiss-Prot: Q5VZI3.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
9号染色体由约1亿4500万个碱基和4%个人类基因组组成，编码近900个基因。考虑到在性别决定中起作用，9p末端的缺失可导致男女性反转，即具有男性X，Y基因型的女性的表型。遗传性出血性毛细血管扩张症以有害的血管缺陷为特征，与编码内皮素蛋白的9号染色体基因ENG相关。家族性自主神经障碍也通过IKBKAP基因与9号染色体相关。值得注意的是，9号染色体包含最大的干扰素家族基因簇。染色体9与22号染色体一起发生易位，导致白血病中常见的BCR-ABL融合蛋白的异常产生。C9OFF91基因产物已暂时指定为C9OFF91，有待进一步鉴定。有三种异构体的C9OFF91，产生作为替代剪接事件的结果。