Anti-HSPB2/FITC Conjugated抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-HSPB2/FITC Conjugated抗体

Anti-HSPB2/FITC Conjugated抗体

商家询价

产品名称: Anti-HSPB2/FITC Conjugated抗体

英文名称: Anti-HSPB2/FITC

产品编号: YB--4782R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-HSPB2/FITC Conjugated抗体

产品编号 YB-4782R-FITC
英文名称 Anti-HSPB2/FITC
中文名称 FITC标记的热休克蛋白B2抗体
别    名 DMPK-binding protein; Heat shock 27kD protein 2; Heat shock 27kDa protein 2; Heat shock protein beta-2; Heat-shock protein beta-2; Hs.78846; HSP27; HspB2; HSPB2_HUMAN; LOH11CR1K; MGC133245; MKBP.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from hu HSPB2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB2 (heat shock 27 kDa protein 2), also known as HSP 27 or MKBP, is a 182 amino acid protein that belongs to the heat shock protein family and is expressed preferentially in heart and skeletal muscle. Localized to mitochondria, HSPB2 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also interact with the Actin cytoskeleton and prevent apoptotic cell death. HSPB2 is abundantly expressed in several cancer cell lines, suggesting that HSPB2 may be an important factor in tumor transformation and metastasis.

Function:
May regulate the kinase DMPK.

Subunit:
Interacts with DMPK; may enhance its kinase activity. 

Subcellular Location:
Cytoplasm. Nucleus. Localizes to nuclear foci.

Tissue Specificity:
Expressed preferentially in skeletal muscle and heart.

Similarity:
Belongs to the small heat shock protein (HSP20) family.

Database links:

Entrez Gene: 508671 Cow

Entrez Gene: 611362 Dog

Entrez Gene: 100736126 Guinea pig

Entrez Gene: 101828097 Hamster

Entrez Gene: 3316 Human

Entrez Gene: 69253 Mouse

Entrez Gene: 100520143 Pig

Entrez Gene: 161476 Rat

Omim: 602179 Human

SwissProt: Q16082 Human

SwissProt: Q99PR8 Mouse

SwissProt: O35878 Rat

Unigene: 709660 Human

Unigene: 1980 Mouse

Unigene: 22486 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicationS