B4GALT7 purified MaxPab mouse polyclonal antibody (B01P)
产品名称: B4GALT7 purified MaxPab mouse polyclonal antibody (B01P)
英文名称: B4GALT7 purified MaxPab mouse polyclonal antibody (B01P)
产品编号: H00011285-B01P
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: 2023-09-20T22:16:01
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human B4GALT7 protein.
- Immunogen:
- B4GALT7 (NP_009186.1, 1 a.a. ~ 327 a.a) full-length human protein.
- Sequence:
- MFPSRRKAAQLPWEDGRSGLLSGGLPRKCSVFHLFVACLSLGFFSLLWLQLSCSGDVARAVRGQGQETSGPPRACPPEPPPEHWEEDASWGPHRLAVLVPFRERFEELLVFVPHMRRFLSRKKIRHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFPEAGPFHVASPELHPLYHYKTYVGGILLLSKQHYRLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPSGITTGYKTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYHVASRTALSVGGAPCTVLNIMLDCDKTATPWCTFS
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
- Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of B4GALT7 expression in transfected 293T cell line (H00011285-T01) by B4GALT7 MaxPab polyclonal antibody.
Lane 1: B4GALT7 transfected lysate(35.97 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 11285
- GeneBank Accession#:
- NM_007255.1
- Protein Accession#:
- NP_009186.1
- Gene Name:
- B4GALT7
- Gene Alias:
- B4GAL-T7,XGALT-1,XGALT1,XGPT1,beta4Gal-T7
- Gene Description:
- xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) linkage found in proteoglycans. Manganese is required as a cofactor. This enzyme differs from the other six beta4GalTs because it lacks the conserved beta4GalT1-beta4GalT6 Cys residues and it is located in cis-Golgi instead of trans-Golgi. Two single-nucleotide mutations were identified from a patient with the progeroid type of Ehlers-Danlos syndrome. [provided by RefSeq
- Other Designations:
- beta-1,4-galactosyltransferase 7,galactosyltransferase 1 (xylosylprotein 4-beta-galactosyltransferase),xylosylprotein beta 1,4-galactosyltransferase 7