Anti-MRGPRX4/FITC Conjugated抗体
产品名称: Anti-MRGPRX4/FITC Conjugated抗体
英文名称: Anti-MRGPRX4/FITC
产品编号: YB--17761R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
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Anti-MRGPRX4/FITC Conjugated抗体
产品编号 | YB-17761R-FITC |
英文名称 | Anti-MRGPRX4/FITC |
中文名称 | FITC标记的MRGPRX4蛋白抗体 |
别 名 | G protein coupled receptor MRGX4; G protein coupled receptor SNSR5; G protein coupled receptor SNSR6; GPCR; Mas related G protein coupled receptor member X4; Mas related G protein coupled-receptor family, member X4; MAS related GPR, member X4; Mas-related G-protein coupled receptor member X4; MGC129753; MGC129754; MRGPRX4; MRGX4; MRGX4_HUMAN; Sensory neuron specific G protein coupled receptor 5/6; Sensory neuron-specific G-protein coupled receptor 5/6; SNSR5; SNSR6. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 G蛋白偶联受体 G蛋白信号 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 36kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MRGPRX4 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
产品介绍 | background: Mas-related G protein-coupled receptor member X1 (MRGX) is a sensory neuron-specific G protein-coupled receptor that is involved in the function of nociceptive neurons. This integral membrane protein may also regulate nociceptor development and/or the sensation or modulation of pain. There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G?q- and G?i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G?q-regulated pathways. G?q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons. Function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Subcellular Location: Cell membrane. Tissue Specificity: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. Database links: Entrez Gene: 117196 Human Omim: 607230 Human SwissProt: Q96LA9 Human Unigene: 632138 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |