FITC标记的转录因子9抗体
产品名称： FITC标记的转录因子9抗体
英文名称： Anti-TCF9/FITC
产品编号： HZ-9812R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-TCF9/FITC Conjugated antibody
FITC标记的转录因子9抗体
| 产品编号 | bs-9812R-FITC |
| 英文名称 | Anti-TCF9/FITC |
| 中文名称 | FITC标记的转录因子9抗体 |
| 别 名 | Chromosome 2 open reading frame 3; DNABF; GC rich sequence DNA binding factor; GC-rich sequence DNA-binding factor; GCF; TCF 9; TCF9; Transcription factor 9; GCFC2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 89kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TCF9/GCF |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: GCF, also known as C2orf3 (chromosome 2 open reading frame 3), transcription factor 9 (TCF-9) or DNABF, is a 781 amino acid nuclear protein that belongs to the GCF family. Widely expressed, GCF binds the GC-rich sequences of ∫-Actin, EGFR and calcium-dependent protease (CANP) promoters. GCF contains multiple phosphoserine and phosphothreonine residues, and two GCF isoforms are produced due to alternative splicing events. GCF is considered a candidate for susceptibility to dyslexia (DYX3) as both genes reside in close proximity on human chromosome 2. Chromosome 2 is the second largest human chromosome and consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. Function: Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Subcellular Location: Nuclear. Tissue Specificity: Widely expressed in tissues and cell lines. Similarity: Belongs to the GCF family. Database links: Entrez Gene: 6936 Human Omim: 189901 Human SwissProt: P16383 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
GCF，也称为C2Orf3（第2染色体开放阅读框3）、转录因子9（TCF-9）或DNABF，是属于GCF家族的781氨基酸核蛋白。广泛表达，GCF结合富含GC序列的肌动蛋白，表皮生长因子受体和钙依赖性蛋白酶（CANP）启动子。GCF含有多种磷酸丝氨酸和磷酸苏氨酸残基，并且由于选择性剪接事件而产生两种GCF异构体。GCF被认为是阅读障碍（DYX3）易感的候选者，因为这两个基因都位于人类染色体2的近处。第2号染色体是第二大人类染色体，由2亿3700万个碱基组成，编码超过1400个基因，约占人类基因组的8%。