FITC标记的叉头蛋白B1+B2抗体
产品名称： FITC标记的叉头蛋白B1+B2抗体
英文名称： Anti-FOXB1 + FOXB2/FITC
产品编号： HZ-11556R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FOXB1 + FOXB2/FITC Conjugated antibody
FITC标记的叉头蛋白B1+B2抗体
| 产品编号 | bs-11556R-FITC |
| 英文名称 | Anti-FOXB1 + FOXB2/FITC |
| 中文名称 | FITC标记的叉头蛋白B1+B2抗体 |
| 别 名 | FOXB1+FOXB2; FKH5; forkhead box B2; Forkhead box protein B1; Forkhead box protein B2; Transcription factor FKH 5; FOXB1_HUMAN; FOXB2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 神经生物学 信号转导 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35, 45kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FOXB1 + FOXB2 (51-100aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: FOXB1 and FOXB2 are winged helix/forkhead transcription factors. FOXB1 is specifically expressed in the developing central nervous system (CNS). Early embryonic FOXB1 expression is restricted to the mammiliary body region of the caudal hypothalamus, midbrain, hindbrain and spinal cord. FOXB1 may play a role in postnatal growth, lactation and CNS development. Function: The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function. Subcellular Location: Nuclear Similarity: Contains 1 fork-head DNA-binding domain. Database links: UniProtKB/Swiss-Prot: Q99853.3 UniProtKB/Swiss-Prot: Q5VYV0.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
FXB1和FXB2是翼螺旋/叉头转录因子。FXB1在发育中的中枢神经系统（CNS）中特异表达。早期胚胎FXB1的表达仅限于尾部下丘脑、中脑、后脑和脊髓的乳头体区域。FXB1可能在出生后的生长、泌乳和中枢神经系统发育中发挥作用。