PFKFB2 (Human) Recombinant Protein (P01)
产品名称： PFKFB2 (Human) Recombinant Protein (P01)
英文名称： PFKFB2 (Human) Recombinant Protein (P01)
产品编号： H00005208-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： 2023-09-19T18:58:31
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PFKFB2 full-length ORF ( NP_006203.2, 1 a.a. - 505 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSPLRAQDMQEGAD
- Theoretical MW (kDa):
- 84.9
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 5208
- GeneBank Accession#:
- NM_006212.2
- Protein Accession#:
- NP_006203.2
- Gene Name:
- PFKFB2
- Gene Alias:
- DKFZp781D2217,MGC138308,MGC138310,PFK-2/FBPase-2
- Gene Description:
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- Omim ID:
- 171835
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2,6PF-2-K/Fru-2,6-P2ASE heart-type isozyme,OTTHUMP00000034285,OTTHUMP00000034286,PFKFB, cardiac,fructose-2,6-bisphosphatase, cardiac isozyme
- Gene Pathway