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上海信裕生物科技有限公司
PRDX1抗体

PRDX1抗体

商家询价

产品名称: PRDX1抗体

英文名称: PRDX1Antibody

产品编号: XY15816-1-

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

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 PRDX1抗体Applications

Tested Applications: ELISA, WB, IF, IHC, IP, FC
Cited applications WB
Specificity Reaction: Human, Mouse, Rat; Other species are not tested.Please decide the specificity by homology
Cited species Human, mouse
Positive WB detected in HEK-293 cells, A549 cells, HeLa cells, MCF7 cells, mouse kidney tissue, NIH/3T3 cells, Raji cells, rat kidney tissue, RAW 264.7 cells
Positive IP detected in HeLa cells
Positive IHC detected in Human breast cancer tissue, human brain tissue
Positive IF detected in HepG2 cells, RAW 264.7 cells
Positive FC detected in HepG2 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100
FC : N/A
 PRDX1抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev12NextView more validation data
  • 15816-1-AP;HEK-293 cellsHEK-293 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP(PRDX1 antibody) at dilution of 1:1000
  • 15816-1-AP;human breast cancerImmunohistochemistry of paraffin-embedded human breast cancer slide using 15816-1-AP( PRDX1 Antibody) at dilution of 1:50
  • 15816-1-AP;human breast cancerImmunohistochemistry of paraffin-embedded human breast cancer slide using 15816-1-AP( PRDX1 Antibody) at dilution of 1:50
  • 15816-1-AP;HepG2 cellsImmunofluorescent analysis of HepG2 cells using 15816-1-AP( PRDX1 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
  • 15816-1-AP;HeLa cellsIP Result of anti-PRDX1 (IP:15816-1-AP, 3ug; Detection:15816-1-AP 1:1000) with HeLa cells lysate 2400ug.
  • 15816-1-AP;HepG2 cells1X10^6 HepG2 cells were stained with 0.2ug PRDX1 antibody (15816-1-AP, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
Product Information PRDX1抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: PRDX1 fusion protein ag8602 Full Name: Peroxiredoxin 1
Caculated Molecular
Weight:
199aa,22 kDa Observed Molecular 
Weight:
23 kDa
GenbankNo BC007063 GeneID: 5052
Symbol PRDX1 Synonyms MSP23, NKEF A, NKEFA, PAG, PAGA, PAGB, peroxiredoxin 1, PRDX1, PRX1, PRXI, TDPX2, Thioredoxin peroxidase 2
Background

PRDX1(Peroxiredoxin-1) is a thiol reductase that plays critical roles in oxidative and thermal stress defense mechanisms through its abilities to metabolize H2O2 and act as a molecular chaperone, respectively.PRDX1 also reduces intramolecular cystine bridges .It can form a dimer(PMID:22583657).It also can be phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity(PMID:11986303). PRDX1抗体

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