Anti-NOL12/NOP25抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-NOL12/NOP25抗体

Anti-NOL12/NOP25抗体

商家询价

产品名称: Anti-NOL12/NOP25抗体

英文名称: NOL12/NOP25

产品编号: YB--19309R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-NOL12/NOP25抗体

产品编号 YB-19309R
英文名称 NOL12/NOP25
中文名称 核仁蛋白12抗体
别    名 C78541; dJ37E16.7; FLJ34609; MGC3731; Nol12; NOL12_HUMAN; Nop25; Nucleolar protein 12; Nucleolar protein of 25 kDa.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NOL12/NOP25:121-213/213 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Nop25 is a 213 amino acid protein that localizes to the nucleolus and is thought to bind to 28S rRNA, possibly playing a role in the processing of rRNA molecules and in the subsequent assembly and maturation of ribosomes. The gene encoding Nop25 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Function:
May bind to 28S rRNA.

Subcellular Location:
Nucleus > nucleolus.

Similarity:
Belongs to the RRP17 family.

SWISS:
Q9UGY1 

Gene ID:
79159

Database links:

Entrez Gene: 79159 Human

Entrez Gene: 97961 Mouse

Entrez Gene: 362955 Rat

SwissProt: Q9UGY1 Human

SwissProt: Q8BG17 Mouse

SwissProt: Q5D1Z3 Rat

Unigene: 632778 Human

Unigene: 157216 Mouse

Unigene: 17454 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.