COL3A1 monoclonal antibody, clone COL-29
产品名称： COL3A1 monoclonal antibody, clone COL-29
英文名称： COL3A1 monoclonal antibody, clone COL-29
产品编号： MAB1514
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native COL3A1.
- Immunogen:
- Native purified human COL3A1.
- Host:
- Mouse
- Theoretical MW (kDa):
- 70
- Reactivity:
- Human, Mouse, Rat
- Form:
- Lyophilized
- Purification:
- Affinity purification
- Isotype:
- IgG1
- Storage Buffer:
- Lyophilized from 1.2% sodium acetate (2 mg BSA, 0.01 mg sodium azide)
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with 1 mL of 1.2% sodium acetate or neutral PBS and concentration will be 100 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Native Purified Protein.
- Recommend Usage:
- Western Blot (0.25-0.5 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
Immunohistochemistry (Frozen sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development.
Liu X, Wu H, Byrne M, Krane S, Jaenisch R.Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1852-6.
- 2.
- Physical mapping by PFGE localizes the COL3A1 and COL5A2 genes to a 35-kb region on human chromosome 2.
Cutting GR, McGinniss MJ, Kasch LM, Tsipouras P, Antonarakis SE.Genomics. 1990 Oct;8(2):407-10.
- Entrez GeneID:
- 1281
- Gene Name:
- COL3A1
- Gene Alias:
- EDS4A,FLJ34534
- Gene Description:
- collagen, type III, alpha 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish
- Other Designations:
- Ehlers-Danlos syndrome type IV, autosomal dominant,alpha1 (III) collagen,collagen type III alpha 1,collagen, fetal
- Gene Pathway
- Related Disease
- Aneurysm, Dissecting
- Angina, Unstable
- Aortic Aneurysm, Abdominal
- Aortic Aneurysm, Thoracic
- Aortic Rupture
- Cardiovascular Diseases
- Chorioamnionitis
- Connective Tissue Diseases
- Coronary Disease
- Cystocele
- Diabetes Mellitus, Type 2
- Edema
- Fetal Diseases
- Fetal Membranes, Premature Rupture
- Gastroesophageal Reflux
- Genetic Predisposition to Disease
- Hemorrhage
- Hepatitis B, Chronic
- Hernia, Hiatal