This antibody is expected to recognize both reported isoforms (NP_005373.2; NP_001099011.1).Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.Store at -20°C.Aliquot to avoid repeated freezing and thawing. *   http://www.creative-diagnostics.com/Anti-NEFM-PAb-190193-147.htm