Anti-SKIP抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-SKIP抗体

Anti-SKIP抗体

商家询价

产品名称: Anti-SKIP抗体

英文名称: SKIP

产品编号: YB--17506R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-SKIP抗体

产品编号 YB-17506R
英文名称 SKIP
中文名称 SKIP蛋白抗体
别    名 43 kDa form skeletal muscle and kidney enriched inositol phosphatase; Inositol polyphosphate 5-phosphatase K; INP5K_HUMAN; INPP5K; muscle and kidney-enriched inositol phosphatase; PPS; skeletal muscle and kidney enriched inositol phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  信号转导  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SKIP:201-300/448 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

Function:
Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negatively regulate assembly of the actin cytoskeleton.

Subcellular Location:
Endoplasmic reticulum. Following stimulation with EGF, translocates to membrane ruffles.

Tissue Specificity:
Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.

Similarity:
Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.

SWISS:
Q9BT40

Gene ID:
51763

Database links:

Entrez Gene: 51763 Human

Entrez Gene: 19062 Mouse

Entrez Gene: 287533 Rat

Omim: 607875 Human

SwissProt: Q9BT40 Human

SwissProt: Q8C5L6 Mouse

Unigene: 632238 Human

Unigene: 1458 Mouse

Unigene: 7440 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications