USP1 polyclonal antibody
产品名称： USP1 polyclonal antibody
英文名称： USP1 polyclonal antibody
产品编号： PAB3912
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of USP1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human USP1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Human and mouse proteases: a comparative genomic approach.
Puente XS, Sanchez LM, Overall CM, Lopez-Otin C.Nat Rev Genet. 2003 Jul;4(7):544-58.
- 2.
- Identification and chromosomal assignment of USP1, a novel gene encoding a human ubiquitin-specific protease.
Fujiwara T, Saito A, Suzuki M, Shinomiya H, Suzuki T, Takahashi E, Tanigami A, Ichiyama A, Chung CH, Nakamura Y, Tanaka K.Genomics. 1998 Nov 15;54(1):155-8.
- 3.
- Deubiquitinating enzymes: a new class of biological regulators.
D'Andrea A, Pellman D.Crit Rev Biochem Mol Biol. 1998;33(5):337-52.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of USP1 polyclonal antibody (Cat # PAB3912) in HepG2 cell line lysate (35 ug/lane). USP1 (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution)
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with USP1 polyclonal antibody (Cat # PAB3912) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
- Entrez GeneID:
- 7398
- Protein Accession#:
- NP_003359;O94782
- Gene Name:
- USP1
- Gene Alias:
- UBP
- Gene Description:
- ubiquitin specific peptidase 1
- Omim ID:
- 603478
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq
- Other Designations:
- OTTHUMP00000010530,deubiquitinating enzyme 1,ubiquitin carboxyl terminal hydrolase 1,ubiquitin specific processing protease 1,ubiquitin specific protease 1,ubiquitin thiolesterase 1