分子量：Calculated MW: 11kDa/34kDa/43kDa/52kDa/55kDa/59kDa/62kDa
Observed MW: 49kDa

细胞定位：Cytoplasm, Endoplasmic reticulum, Nucleus, nucleolus

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200

总结：Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.